HYPERTHERMIA TREATMENT SIMULATION USING 3D OCTREE MESHES

Andre Valente¹; Leandro Di Bartolo²; Felipe Loureiro³; Webe Mansur⁴

¹ IFRJ; ² Observatório Nacional; ³ Universidade Federal de São João Del Rei; ⁴ UFRJ-COPPE

doi:10.20906/CPS/CILAMCE2017-0136

Resumo

Hyperthermia treatment for cancer are becoming increasingly more common. However, the thermal ablation procedures have a main limiting factor: the correct increase of the temperature in the living tissue, which in some cases can cause undesirable effects such as irreversible damages in the healthy tissue. This paper presents the development of a FVM-based formulation using OcTree meshes that aims to simulate the hyperthermia treatment by injection of nanoparticles. A 3D linear Pennes' model is employed to simulate the heat transfer in blood perfused living tissues with a tumor. The OcTree mesh is used due to its simplicity in griding and, at the same time, allowing local refinement using a nonconforming mesh. A simple numerical example is analyzed, validating the proposed algorithm and showing the efficiency of the proposed scheme.

Palavras-chave: Pennes bioheat model; Finite-volume method ; OcTree; Hyperthermia; Nanoparticles